Divorce

-Divorce can have a huge impact on the family, such as financial disputes for child support, siblings separated, and more

Absenteeism of parents

-Absenteeism of parents affects the parent's children more, as they won't have the parental support needed for growth

Parental Abuse

-An abusive parent or spouse greatly impacts the family as it can cause mental health issues and disconnection as a family

Parental Neglect

-Parental neglect affects the parent's children more than the parents themselves in most cases since the child's basic needs and/or wants aren't being met.

[Sorry, but I cannot give an answer for "same-sex marriage" as it being part of this list of "issues" is quite homophobic. (I'm a Minsexual-demisexual so of course, I refuse to answer a homophobic question about Same-sex marriage being an 'issue')]