The Gabriel synthesis involves reacting a primary alkyl halide with potassium phthalimide to form an alkyl phthalimide. Subsequent base treatment and nucleophilic substitution lead to the alkyl phthalimide. Hydrolysis removes the phthalimide group, resulting in the formation of a primary amine ..
What is Gabriel phthalimide reaction? The Gabriel synthesis is a chemical reaction that transforms primary alkyl halides into primary amines. Traditionally, the reaction uses potassium phthalimide. The name of the reaction comes from the German chemist Siegmund Gabriel.
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Explanation:
What is Gabriel phthalimide reaction? The Gabriel synthesis is a chemical reaction that transforms primary alkyl halides into primary amines. Traditionally, the reaction uses potassium phthalimide. The name of the reaction comes from the German chemist Siegmund Gabriel.