What is centromere?,
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the region of a chromosome to which the microtubules of the spindle attach, via the kinetochore, during cell division.
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The centromere is the specialized DNA sequence of a chromosome that links a pair of sister chromatids. During mitosis, spindle fibers attach to the centromere via the kinetochore. Centromeres were first thought to be genetic loci that direct the behavior of chromosomes.