First up, let's clearly understand what Placebo and Statin exactly are :

Statins :

• Statins are bio active molecules which reduce the blood cholesterol levels by inhibiting the production of Coenzyme A.
• Statins are derived from secretions of Monascus purpureus.
• Action of statins is an example of Competitive Inhibition, as levels of coenzymeA directly affect the levels of cholesterol.

Placebo Effect :

• Intake of hallucinogens rather than the actual medicines is termed as Placebo.
• Placebo has psychological effects and doesn't help in treating the underlying symptoms. In short, one will feel better but the disease would still persist. It's called 'dummy medicine' for a reason.

For trails, any approach involving placebo is a failure if aim of the experiment is to bring cholesterol levels under control. Then approach A would have been the most effective if we were to ignore the regressive consequences.

Since, the aim of the trail is to test the potence of the statin, some samples for removing the anomalies would be required. Eliminating Option (A).

Metabolic Pathways vary significantly between both the sexes, meaning that statin will respond in different ways under different conditions. Thus, limiting the dosage of statin to one gender should affect the results. Eliminating Option (C).

Action of statin could will vary depending on the conditions. Limiting patients to same treatment would block the effectiveness check, for instance, I would be curious to observe the action of statin on a patient who was earlier treated with Placebo. Eliminating Option (D).

Option (B) is correct.

Answer:

The above question is based on Scholastic aptitude where a survey was done to identify the effectiveness of a group of medicines by the help of a randomly chosen people suffering with high cholesterol. Need help, Kinda confused! :D

Please include the correct answer, explain why you chose that approach and deleted the others. Have a good answering time✌️

#BeBrainly~