B.125

Step-by-step explanation:

All these numbers are the cube of consecutive numbers ,the cube of 1 is 1, the cube of 2 is 8 ,3 is 27 ,4 is 64 and so the next number which is 5 , it's cube will be 125 and so the series will be 1, 8, 27, 64, 125 ,216 and so on…

Answer:

The missing number in the sequence 1, 8, 27, __, 125, 216 is '64' which follows ascending cubes.

in other words

letter C