Helicase unwinds the helix, and single-strand binding proteins prevent the helix from re-forming. ... Single-strand binding proteins coat the DNA around the replication fork to prevent rewinding of the DNA. Topoisomerase works at the region ahead of the replication fork to prevent supercoiling.
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Answer:
Helicase unwinds the helix, and single-strand binding proteins prevent the helix from re-forming. ... Single-strand binding proteins coat the DNA around the replication fork to prevent rewinding of the DNA. Topoisomerase works at the region ahead of the replication fork to prevent supercoiling.
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