The blood–brain barrier acts effectively to protect the brain from circulating pathogens. The blood–brain barrier becomes more permeable during inflammation, potentially allowing antibiotics and phagocytes to move across the BBB. The brain's blood vessels are lined with endothelial cells that are wedged tightly together, creating a nearly impermeable boundary between the brain and bloodstream.
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The blood–brain barrier acts effectively to protect the brain from circulating pathogens. The blood–brain barrier becomes more permeable during inflammation, potentially allowing antibiotics and phagocytes to move across the BBB. The brain's blood vessels are lined with endothelial cells that are wedged tightly together, creating a nearly impermeable boundary between the brain and bloodstream.