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In Hinduism, Mathura is believed to be the birthplace of Krishna, which is located at the Krishna Janmasthan Temple Complex. It is one of the Sapta Puri, the seven cities considered holy by Hindus. The Kesava Deo Temple was built in ancient times on the site of Krishna's birthplace (an underground prison). Mathura was the capital of the kingdom of Surasena, ruled by Kansa, the maternal uncle of Krishna. Janmashtami is grandly celebrated in Mathura every year.

Mathura has been chosen as one of the heritage cities for the Heritage City Development and Augmentation Yojana scheme of Government of India