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Christianity in the Middle Ages covers the history of Christianity from the Fall of the Western Roman Empire (c. 476). The end of the period is variously defined. Depending on the context, events such as the conquest of Constantinople by the Ottoman Empire in 1453, Christopher Columbus's first voyage to the Americas in 1492, or the Protestant Reformation in 1517 are sometimes used.[1]

Brothers Cyril and Methodius bring Christianity to the Slavic peoples.

In Christianity's ancient Pentarchy, five patriarchies held special eminence: the sees of Rome, Constantinople, Jerusalem, Antioch, and Alexandria. The prestige of most of these sees depended in part on their apostolic founders, or in the case of Byzantium/Constantinople, that it was the new seat of the continuing Eastern Roman, or Byzantine Empire. These bishops considered themselves the successors of those apostles.[2] In addition, all five cities were early centres of Christianity, they lost their importance after the Levant was conquered by the Sunni Caliphate.