Glycolysis is a metabolic pathway that occurs in the cytosol of cells and converts glucose into two molecules of pyruvate. The primary function of glycolysis is to generate energy in the form of ATP. It is a central pathway that occurs in most organisms and plays a key role in metabolism.
Here are some major features of glycolysis:
1. Glycolysis is an anaerobic process, meaning it does not require oxygen to occur.
2. It involves the breakdown of a single molecule of glucose into two molecules of pyruvate, with the generation of ATP and NADH.
3. Glycolysis is regulated by several enzymes, including hexokinase, phosphofructokinase, and pyruvate kinase.
4. It can be divided into two stages: the energy-investment phase, which requires the input of ATP, and the energy-yielding phase, which generates ATP.
5. In the presence of oxygen, pyruvate produced during glycolysis is further oxidized through the citric acid cycle (also known as the Krebs cycle) to generate additional ATP.
Some important events in glycolysis include:
1. The conversion of glucose to glucose-6-phosphate by hexokinase, which is the first committed step of glycolysis.
2. The conversion of fructose-6-phosphate to fructose-1,6-bisphosphate by phosphofructokinase, which is a rate-limiting enzyme in glycolysis.
3. The breakdown of glyceraldehyde-3-phosphate to pyruvate by glyceraldehyde-3-phosphate dehydrogenase, which generates NADH.
4. The conversion of pyruvate to acetyl-CoA by pyruvate dehydrogenase, which is the terminal step of glycolysis and occurs in the mitochondria.
Answers & Comments
Answer:
Glycolysis is a metabolic pathway that occurs in the cytosol of cells and converts glucose into two molecules of pyruvate. The primary function of glycolysis is to generate energy in the form of ATP. It is a central pathway that occurs in most organisms and plays a key role in metabolism.
Here are some major features of glycolysis:
1. Glycolysis is an anaerobic process, meaning it does not require oxygen to occur.
2. It involves the breakdown of a single molecule of glucose into two molecules of pyruvate, with the generation of ATP and NADH.
3. Glycolysis is regulated by several enzymes, including hexokinase, phosphofructokinase, and pyruvate kinase.
4. It can be divided into two stages: the energy-investment phase, which requires the input of ATP, and the energy-yielding phase, which generates ATP.
5. In the presence of oxygen, pyruvate produced during glycolysis is further oxidized through the citric acid cycle (also known as the Krebs cycle) to generate additional ATP.
Some important events in glycolysis include:
1. The conversion of glucose to glucose-6-phosphate by hexokinase, which is the first committed step of glycolysis.
2. The conversion of fructose-6-phosphate to fructose-1,6-bisphosphate by phosphofructokinase, which is a rate-limiting enzyme in glycolysis.
3. The breakdown of glyceraldehyde-3-phosphate to pyruvate by glyceraldehyde-3-phosphate dehydrogenase, which generates NADH.
4. The conversion of pyruvate to acetyl-CoA by pyruvate dehydrogenase, which is the terminal step of glycolysis and occurs in the mitochondria.
Explanation:
hope this explanation helps