Using single-lensed microscopes of his own design and make, van Leeuwenhoek was the first to observe and to experiment with microbes, which he originally referred to as dierkens, diertgens or diertjes (Dutch for "small animals" [translated into English as animalcules, from Latin animalculum = "tiny animal"]).
In the 1660s, Robert Hooke looked through a primitive microscope at a thinly cut piece of cork. He saw a series of walled boxes that reminded him of the tiny rooms, or cellula, occupied by monks. Medical historian Dr. Howard Markel discusses Hooke's coining of the word "cell."
The third part, which asserts that cells come from preexisting cells that have multiplied, was described by Rudolf Virchow in 1858, when he stated omnis cellula e cellula (all cells come from cells).
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